arXiv:2604.15279v2 Announce Type: replace Abstract: Hybrid High-performance Computing (HPC)-quantum workloads based on circuit cutting decompose large quantum circuits into independent fragments, but existing frameworks tightly couple cutting logic to execution orchestration, preventing HPC centers from applying mature resource management policies to Noisy Intermediate-Scale Quantum (NISQ) workloads. We present DQR (Dynamic Queue Router), a runtime framework that bridges this gap by treating circuit fragments as first-class schedulable units. The framework introduces a backend-agnostic fragment descriptor to expose structural properties without requiring execution layers to parse quantum code, a wave-based coordinator that achieves pipeline concurrency via non-blocking polling, and a production-ready implementation on the CESGA Qmio supercomputer integrating both QPUs local on-premises (Qmio) and remote cloud (IBM Torino) backends. Experiments on a 32-qubit Hardware-Efficient Ansatz (HEA) circuit demonstrate not only makespan improvements over a monolithic CPU baseline but also transparent per-fragment failover recovery-specifically rerouting tasks from the local QPU to classical simulators upon encountering hardware-level incompatibilities-without pipeline restart. For deeper circuits, the coordination residual accounts for only 5% of the total execution time, highlighting the framework's scalability. These results show that DQR enables HPC centers to integrate NISQ workloads into existing production infrastructure while preserving the flexibility to adopt improved cutting algorithms or heterogeneous backend technologies.