NRF2 is a mechanosensitive checkpoint for NLRP3 inflammasome activation

Nature News2026-11-12 01:030 views

Nature, Published online: 11 November 2026; doi:10.1038/s41586-026-11324-7

The stiffness of the extracellular matrix is identified as a pivotal factor that influences activation of the NLRP3 inflammasome in vitro and in vivo.

Source：https://www.nature.com/articles/s41586-026-11324-7

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NRF2 is a mechanosensitive checkpoint for NLRP3 inflammasome activation

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